A previous study had demonstrated that the cells with mutations in the p53 gene are less sensitive to many standard chemotherapeutic agents that induce DNA damage, suggesting that the cellular ...
It causes mutations in the p53 tumor-suppressor gene as well as ras mutations, which are involved in the majority of human cancers. Aflatoxin has been shown to contaminate tobacco products.
Researchers have elucidated the role of the p53 gene in ulcerative colitis. The study suggests a potential new drug target to stop disease progression to cancer.
New research highlights a pivotal role for the p53 gene in ulcerative colitis progression, offering a potential therapeutic ...
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Researchers uncover why the TP53 gene is especially prone to mutations in cancerBy Dr. Sushama R. Chaphalkar, PhD. The fragile structure of p53 gene reveals why this crucial cancer defense is so easily ...
The study was published in the journal Science Advances. ‘Researchers have identified the role of the p53 gene in #ulcerativecolitis, paving the way for potential new treatments to prevent # ...
Enrollment on track in Phase 2 portion of PYNNACLE clinical trial evaluating rezatapopt as monotherapy in patients with TP53 Y220C and KRAS ...
UC Santa Barbara anthropologist Amy Boddy and her collaborators are working to gain insight on this and other cancer ...
The results of research headed by a team in the lab of Michael Sigal, MD, at the Max Delbrück Center and Charité—Universitätsmedizin Berlin, have shed new light on the role of the p53 tumor ...
A gene mutation, or change, can make this happen. Cells normally divide, grow, and may die, at set times. But a gene that changes in a certain way can trigger cells to continue to divide and grow ...
About PMV Pharma PMV Pharma is a precision oncology company pioneering the discovery and development of small molecule, tumor-agnostic therapies targeting p53. TP53 mutations are found in ...
About PMV Pharma PMV Pharma is a precision oncology company pioneering the discovery and development of small molecule, tumor-agnostic therapies targeting p53. TP53 mutations are found in ...
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