Gavin Sheets hit two of San Diego's four home runs and drove in four runs, and Fernando Tatis Jr. robbed Giant's Rafael Devers of a homer.

A disastrous fifth inning doomed the Giants in San Francisco's 8-4 loss to the San Diego Padres on Thursday afternoon at Petco Park.

The San Diego Padres (71-56) and San Francisco Giants (61-66) will meet on Thursday at PETCO Park, with first pitch at 4:10 p.m. ET. The Padres are the home favorite (-139) versus the Giants (+118). The Padres will start Dylan Cease (5-11) against the Giants and Justin Verlander (1-9).

Preview the Aug. 20 matchup between the San Diego Padres and San Francisco Giants with odds over/under, game spread, betting lines and more.

The San Diego Padres took the series over the San Francisco Giants on Thursday, winning three of four games despite playing the entire set without star centerfielder Jackson Merrill. The 22-year-old exited Sunday’s game against the Los Angeles Dodgers early with a bone bruise in his left ankle, after initially tweaking it a couple of games prior.

Petco park erupted in boos after a security guard brutally tackled a San Diego Padres kid who ran out on the field.

The San Francisco Giants, as expected, officially placed Landen Roupp on the 15-day injured list with left knee inflammation on Friday although there remained no word as to how much time the right-handed starting pitcher might be forced to miss.