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DUBAI, United Arab Emirates (AP) — Israel launched an expanded assault on Iran on Sunday, with direct strikes targeting its energy industry and Defense Ministry headquarters, while Tehran unleashed a fresh barrage of missiles blamed for the deaths of four people and injuries of many others.

Iran launched dozens of ballistic missiles toward Israel on Friday night in retaliation for Israel's surprise attack early Friday. Israel struck at the heart of the Iran's nuclear program, killing several nuclear scientists as well as high-ranking military leaders, according to Israeli officials.

The conflict between Israel and Iran - once played out in a series of proxy wars - has escalated. On Friday morning, explosions hit Tehran as Israel carried out a major attack on its nuclear capabilities. Iran threatened "severe punishment" and quickly retaliated with a wave of missiles.

The Israeli military struck "over 170 targets" in Iran in three days, the Israel Defense Forces (IDF) said on Sunday.

"The full strength and might of the U.S. Armed Forces will come down on you at levels never seen before," Trump warned.

The fighting between Israel and Iran intensified on Monday night, as both nations kept up their attacks, killing civilians and raising concern among world leaders that the biggest battle between old enemies could lead to a broad regional conflict.